|
Characteristics
|
Total
|
Aluminum content in mg/Kg
| |
|---|
| | |
Mean (sd)
| |
Negative*
|
0.05 - 2.0
|
≥ 2
| |
|
Age
| | |
P**
|
n
|
(%)
|
n
|
(%)
|
n
|
(%)
|
P trend***
|
|
<40
|
20
|
1.25(1.49)
|
0.12
|
6
|
(17.6)
|
9
|
(11.1)
|
5
|
(14.3)
|
0.68
|
|
>4
0
|
130
|
1.97(3.81)
| |
28
|
(82.4)
|
72
|
(88.9)
|
30
|
(85.7)
| |
|
BMI
| | | | | | | | | | |
|
<25
|
46
|
1.96(2.43)
|
0.74
|
7
|
(28)
|
26
|
(38.2)
|
13
|
(40.6)
|
0.34
|
|
≥25
|
79
|
2.05(4.39)
| |
18
|
(72)
|
42
|
(61.8)
|
19
|
(59.4)
| |
|
Menopausal status
| | | | | | | | | | |
|
Post
|
42
|
1.28(1.32)
|
0.03
|
9
|
(33.3)
|
23
|
(32.9)
|
10
|
(29.4)
|
0.73
|
|
Pre
|
89
|
2.34(4.40)
| |
18
|
(66.7)
|
47
|
(67.1)
|
24
|
(70.6)
| |
|
Quadrant
| | | | | | | | | | |
|
Upper external
|
92
|
1.83(3.61)
|
0.93
|
23
|
(67.6)
|
47
|
(58)
|
22
|
(62.9)
|
0.69
|
|
Other
|
58
|
1.94(3.61)
| |
11
|
(32.4)
|
34
|
(42)
|
13
|
(37.1)
| |
|
Tumor size
| | | | | | | | | | |
|
<2.0 cm
|
72
|
2.36(4.64)
|
0.21
|
13
|
(38.2)
|
39
|
(49.4)
|
20
|
(57.1)
|
0.11
|
|
≥2.0 cm
|
76
|
1.44(2.21)
| |
21
|
(61.8)
|
40
|
(50.6)
|
15
|
(42.9)
| |
|
Stage
| | | | | | | | | | |
|
I-II
|
90
|
2.19(4.37)
|
0.13
|
19
|
(57.6)
|
49
|
(61.3)
|
22
|
(62.9)
|
0.65
|
|
III – IV
|
58
|
1.42(1.90)
| |
14
|
(42.4)
|
31
|
(38.8)
|
13
|
(37.1)
| |
|
Histologic grade
| | | | | | | | | | |
|
I-II
|
26
|
2.36(6.02)
|
0.79
|
5
|
(15.6)
|
17
|
(23)
|
4
|
(12.1)
|
0.70
|
|
III
|
113
|
1.74(2.87)
| |
27
|
(84.4)
|
57
|
(77)
|
29
|
(87.9)
| |
|
Estrogen receptor
| | | | | | | | | | |
|
Negative
|
40
|
1.34(1.48)
|
0.67
|
12
|
(36.4)
|
17
|
(22.4)
|
11
|
(32.4)
|
0.72
|
|
Positive
|
103
|
2.13(4.22)
| |
21
|
(63.6)
|
59
|
(77.6)
|
23
|
(67.6)
| |
|
Progesterone receptor
| | | | | | | | | | |
|
Negative
|
56
|
1.34(1.31)
|
0.86
|
15
|
(45.5)
|
28
|
(36.8)
|
13
|
(39.4)
|
0.61
|
|
Positive
|
86
|
2.25(4.59)
| |
18
|
(54.5)
|
48
|
(63.2)
|
20
|
(60.6)
| |
|
cerbb2 status
| | | | | | | | | | |
|
Negative
|
94
|
1.91(3.54)
|
0.18
|
22
|
(66.7)
|
47
|
(63.5)
|
25
|
(75.8)
|
0.43
|
|
Positive
|
46
|
1.91(4.07)
| |
11
|
(33.3)
|
27
|
(36.5)
|
8
|
(24.2)
| |
-
Note: The aluminum concentration was categorized as negative, 0.05-2.0 mg/ kg and ≥ 2.0 mg/ kg according to the three-tiered percentile distribution of the raw data. *Aluminum detection threshold for the GF-AAS was set at 0.05 mg/kg; ** In this column, the p values refer to the comparison of the mean Aluminum concentrations in each strata, using independent samples t-tests with the log-transformed (to base e) data; ***In this column, the p-values refer to the Chi-squares for trends; i.e. if p ≤ 0.05, there is a significant trend in Aluminum concentration related to the specified characteristic (see statistics for more details).
