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Table 4 Acute hematologic and nonhematologic adverse events during induction chemotherapy and concurrent chemoradiotherapy

From: Multicenter phase II study of weekly docetaxel, cisplatin, and S-1 (TPS) induction chemotherapy for locally advanced squamous cell cancer of the head and neck

 

Grade 1-2

Grade 3-4

 

No.

%

No.

%

Hematologic

    

 Neutropenia

9

25.7

10

28.5

 Neutropenic fever

0

0

3

8.5

 Anemia

22

62.8

1

2.8

 Thrombocytopenia

10

28.5

1

2.8

Nonhematologic

    

 Anorexia/Nausea/Vomiting

26

74.2

4

11.4

 Fatigue/Asthenia

23

65.7

1

2.8

 Mucositis/Odynophagia

15

42.8

3

8.5

 Diarrhea

15

42.8

6

17.1

 Neuropathy

4

11.4

0

0

 Nephropathy

5

14.2

0

0

  1. Note. Adverse events were graded according to the National Cancer Institute Common Toxicity Criteria, version 3.0.