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Table 2 Response to induction chemotherapy and chemoradiation therapy

From: Multicenter phase II study of weekly docetaxel, cisplatin, and S-1 (TPS) induction chemotherapy for locally advanced squamous cell cancer of the head and neck

 

Primary lesion (n = 35)

Lymph node (n = 25)

Response

No.

%

No.

%

  After induction chemotherapy

    

CR

18

51.4

7

28

PR

11

31.4

13

52

SD

1

2.9

1

4

PD

0

0

0

0

 Non-assessable

5

14.2

4

16

 Combined response (Primary lesion + LN)

    

   CR

    

No.

9

%

25.7

 ORR (CR + PR)

    

No.

30

%

85.7

  After Concomitant chemoradiation

    

CR

24

68.6

17

68

PR

6

17.1

4

16

SD

0

0

0

0

PD

0

0

0

0

  Combined response

    

   CR

    

No.

22

%

62.8

 ORR (CR + PR)

    

No.

30

%

85.7

  1. Abbreviations: LN, regional neck lymph nodes; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; ORR, overall response rate.