Table 1 Microsatellite alleles and sequence polimorphisms of mitochondrial DNA hypervariable regions (HV1 and HV2) detected in constitutional DNA, primary tumor and metastasis of ATRT index case
Marker | Costituzional DNA | Primary tumor | Metastatic tumor | Mb position (chr22 start) |
|---|---|---|---|---|
D22S427 | ||||
(22q11.21) | 97 - 97 | 97 | 97 | 18,591,317 |
D22S257 | ||||
(22q11.23) | 120 - 128 | 128 | 128 | 23,568,429 |
D22S1174 | ||||
(22q11.23) | 139 - 141 | 139 | 139 | 24,488,486 |
D22S1154 | ||||
(22q12.1) | 264 - 266 | 264 | 264 | 26,617,527 |
D22S1163 | ||||
(22q12.1) | 148 - 162 | 162 | 162 | 27,918,651 |
HV1 | - | 16183C | 16183C | - |
16189C | 16189C | |||
HV2 | - | 263 G | 263 G | - |
309.3C | 309.3C | |||
315.1C | 315.1C |