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Table 3 Multivariate Cox regression analysis on disease-specific survival in 80 invasive breast cancer patients

From: Elevated cyclin B2 expression in invasive breast carcinoma is associated with unfavorable clinical outcome

Disease specific survival
Characteristics β SE HR 95% CI P-value*
BRE grade 0.14 0.17 1.16 0.83-1.61 0.39
HER2/neu status 0.18 0.40 0.83 0.39-1.80 0.64
Axillary lymph node status 0.03 0.35 1.03 0.53-2.04 0.64
Pathologic tumor size 0.001 0.01 0.10 0.98-1.02 0.97
ER/PR status 0.03 0.35 0.99 0.49-1.95 0.94
CCNB2 1.82 0.61 6.14 1.87-20.1 0.003
  1. * Determined by chi-square test.
  2. β: Regression coefficient; SE: standard error of β; HR: hazard ratio; and CI: confidence interval. BRE: Bloom, Richardson, Elston/ Ellis; ER/PR: Estrogen/progesterone receptor. Coding of characteristics: BRE, HER2/neu status, Axillary lymph node status, ER/PR and CCNB2 were coded as 0 (negative) and 1 (positive) respectively. Pathologic tumor size was coded as 1 (0-20mm), 2 (>20-50mm), and 3 (>50mm).