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Table 3 Multivariate Cox regression analysis on disease-specific survival in 80 invasive breast cancer patients

From: Elevated cyclin B2 expression in invasive breast carcinoma is associated with unfavorable clinical outcome

Disease specific survival

Characteristics

β

SE

HR

95% CI

P-value*

BRE grade

0.14

0.17

1.16

0.83-1.61

0.39

HER2/neu status

0.18

0.40

0.83

0.39-1.80

0.64

Axillary lymph node status

0.03

0.35

1.03

0.53-2.04

0.64

Pathologic tumor size

0.001

0.01

0.10

0.98-1.02

0.97

ER/PR status

0.03

0.35

0.99

0.49-1.95

0.94

CCNB2

1.82

0.61

6.14

1.87-20.1

0.003

  1. * Determined by chi-square test.
  2. β: Regression coefficient; SE: standard error of β; HR: hazard ratio; and CI: confidence interval. BRE: Bloom, Richardson, Elston/ Ellis; ER/PR: Estrogen/progesterone receptor. Coding of characteristics: BRE, HER2/neu status, Axillary lymph node status, ER/PR and CCNB2 were coded as 0 (negative) and 1 (positive) respectively. Pathologic tumor size was coded as 1 (0-20mm), 2 (>20-50mm), and 3 (>50mm).