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Table 2 Correlation analysis of genomic profiles of spiked cells isolated from blood via IE/FACS.

From: Isolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer

Cell Line Source Input for WGA No. of replicates Correlation with positive control S.D.
LNCaP IE/FACS 20 cells 2 0.63 0.15
  Cell culture 50 ng 1 0.82 n.a.
PC3 IE/FACS 20 cells 2 0.88 0.03
  Cell culture 50 ng 1 0.97 n.a.
VCaP IE/FACS 20 cells 2 0.82 0.02
  Cell culture 50 ng 1 0.89 n.a.
  1. Isolated 20 tumor cells (in duplicate) and genomic DNA (50 ng) from cell culture were subjected to WGA and aCGH analysis and compared to positive control: unamplified genomic DNA (600 ng) from cell culture
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