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Table 2 Course of Fatigue, Anxiety and Depression as assessed in 21 ovarian cancer patients with three different assessment instruments

From: Monitoring physical and psychosocial symptom trajectories in ovarian cancer patients receiving chemotherapy

 

BLa

CT2b

CT3

CT4

CT5

CT6

AC1b

AC2

Constant Term/

Beta Coefficient

Reference

Valuesc

Hospital Anxiety and Depression Scale (HADS) c

 

Anxiety

7.0 (4.2)

6.1

4.5

4.5

3.9

4.1

4.5

4.1 (4.3)

5.7/-0.3

t = -2.80; p = 0.006

5.0

(3.4)

Depression

6.5 (3.8)

5.4

3

4.5

3.5

3.3

3.1

2.3 (3.6)

5.2/-0.3

t = -4.07; p < 0.001

4.7

(3.9)

Hamilton Anxiety and Depression Scale (HAMA/D)

 

Anxiety

15.0 (8.0)

11.0

11.4

10.4

8.3

7.5

9.2

7.6 (5.9)

12.8/-0.6

t = -3.01; p = 0.004

n.a.

Depression

11.7 (6.8)

8.1

7.9

7.6

5.6

6.6

5.2

4.7 (3.2)

9.3/-0.6

t = -3.58; p = 0.001

n.a.

Multidimensional Fatigue Inventory (MFI) c

 

General

Fatigue

13.2 (4.7)

13.4

11.9

12.8

11.8

11.7

9.7

7.8 (3.9)

13.4/-0.5

t = -4.62; p < 0.001

10.8

(3.7)

Physical

Fatigue

13.1 (3.9)

13.5

13.4

12.9

11.2

11.2

9.6

7.4 (4.4)

13.7/-0.5

t = -5.29; p < 0.001

11.1

(4.2)

Reduced

Activity

15.4 (4.8)

15.1

12.2

12.4

10.9

11.2

8.7

6.5 (3.6)

15.2/-1.0

t = -8.19; p < 0.001

10.5

(4.0)

Reduced

Motivation

7.5 (3.5)

7.4

6.5

7.9

6.4

6.3

6.2

5.6 (1.9)

7.5/-0.2

t = -2.98; p = 0.004

9.9

(3.5)

Mental

Fatigue

9.8 (5.1)

8.6

8.8

9.6

8.2

7.7

7.5

7.3 (4.3)

9.3/-0.2

t = -2.03; p = 0.046

9.2

(3.4)

  1. a BL baseline (CT1)
  2. b CT chemotherapy cycle, AC aftercare
  3. c Reference values: HADS (female general population) [31]MFI-20 (general population > 60 y) [30]