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Table 2 A summary of confirmatory qRT-PCR analysis of selective genes

From: REGγ is associated with multiple oncogenic pathways in human cancers

Tissue Gene Symbol PCR value p-value Status Gene Annotation
Colon BTG2 1.25 1.5E-02 Consistent A member of the BTG/Tob family
Lung DAPK2 1.35 6.0E-12 Consistent Death-associated protein kinase 1 (DAPK1)
Lung GADD45B 1.63 2.6E-02 Consistent Growth arrest and DNA-damage-inducible
Lung SATB1 2.82 4.3E-04 Consistent SATB homeobox 1
Thyroid ABCA1 1.68 2.8E-02 Consistent ATP-binding cassette, sub-family A
Thyroid B3GALT4 1.32 2.0E-03 Consistent UDP-Gal:betaGlcNAc beta 1,3-
galactosyltransferase
Thyroid PTEN 1.29 4.3E-02 Consistent Phosphatase and tensin homolog, tumor
suppressor
Colon CCT3 0.62 2.9E-03 Consistent Member of the chaperonin
Colon DKC1 0.60 8.3E-04 Consistent Dyskeratosis congenita 1, dyskerin
Colon HSP90AB1 0.82 2.4E-02 Consistent A member of heat shock
Colon MYC 0.57 6.7E-03 Consistent myelocytomatosis viral oncogene homolog
Colon ODC1 0.80 1.3E-02 Consistent A p53 target negatively regulated.
Colon RRM2 0.66 4.0E-02 Consistent ribonucleotide reductase M2
Liver DDB1 0.63 3.6E-02 Consistent Damage-specific DNA binding protein 1
Liver HN1 0.65 1.3E-03 Consistent Hematological and neurological expressed1
Liver ILF2 0.79 5.7E-04 Consistent Interleukin enhancer binding factor 2
Liver RAN 0.75 1.3E-02 Consistent ras-related nuclear protein
Lung BUB3 0.82 8.2E-03 Consistent Budding uninhibited by benzimidazoles 3 homolog
Lung USP14 0.74 2.7E-03 Consistent Ubiquitin specific peptidase 14
Thyroid ATR 0.47 5.6E-03 Consistent Ataxia telangiectasia and Rad3 related
    Total Consistent N = 20 (66.7%)
Conlon ACLY 1.40 3.7E-05 Inconsistent ATP citrate lyase
Thyroid TSC2 2.18 1.4E-05 Inconsistent Tuberous sclerosis 2, tumor suppressor
Colon CDK1 0.50 7.3E-07 Inconsistent Cyclin-dependent kinase 1
Colon SPPL2A 0.38 3.5E-02 Inconsistent Signal peptide peptidase-like 2A
Conlon TUBG1 0.43 8.5E-05 Inconsistent Tubulin, gamma 1
Liver EHHADH 0.61 4.4E-02 Inconsistent Enoyl-CoA, hydratase/dehydrogenase
Liver CYP4F2 0.70 3.2E-02 Inconsistent Cytochrome P450, family 4, subfamily F
Lung STARD8 0.66 7.5E-03 Inconsistent A subfamily of Rho GTPase
Lung UNC13A 4.73 8.2E-06 Inconsistent Unc-13 homolog A
Thyroid PPAP2A 0.63 2.8E-02 Inconsistent Phosphatidic acid phosphatase type 2A
    Total Inconsistent n = 10 (33.3%)
  1. PCR value was the expression level of qRT-PCR results in shR (REGγ depletion) cells relative to that in shN (REGγ expressing) cells (see Figure S4). The results were averaged from three independent experiments