Figure 4
From: REGγ is associated with multiple oncogenic pathways in human cancers
Statistical analysis and functional annotation of genes correlated to REGγ. (A) Distribution of PCC (Pearson correlation coefficient) in datasets from different cancers. Upper panel box-plot shows positive PCC and lower panel displays negative PCC values (Y axis) that are greater than +0.6 or less than -0.6. Analyzed datasets are from colon (n = 3), liver (n = 4), lung (n = 3) and thyroid (n = 3). (B) Most of the annotated REGγ-correlated gene pathways are involved in cancers. Ingenuity analysis of REGγ-correlated gene pathways were grouped into cancer (black, 10%), cancer related (grey, 49%) and other pathway clusters (white, 41%) to reveal the proportion of REGγ-correlated gene pathways in cancers. (C) Most of the annotated REGγ-correlated genes are cancer-related. The genes representing cancer, cancer related and other-pathway clusters were plotted to show the overlaps among different pathway clusters. Note that the total number of cancer and cancer-related genes constitute majority of the REGγ-correlated genes.