Table 5 Concordance between detection of MembErbB-2 expression by immunofluorescence and immunohistochemistry
From: Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer
MembErbB-2 (IFa C-18), n (%) | Total N (%) | Overall concordance (%) | κ statisticsd | ||
|---|---|---|---|---|---|
Negative | Positive | ||||
MembErbB-2 (IHC b RBT HER2) | |||||
Negative | 168 (83.4)c | 7 (3.5) | 175 (87.1) | 96 | 0.84 |
Positive | 1 (0.4) | 25 (12.7) | 26 (12.9) | ||
MembErbB-2 (IHC A0485) | |||||
Negative | 170 (80.9) | 11 (5.2) | 181 (86.2) | 90 | 0.6 |
Positive | 10 (4.8) | 19 (9.1) | 29 (13.8) | ||
MembErbB-2 (IHC C-18) | |||||
Negative | 168 (83.2) | 9 (4.5) | 177 (87.6) | 93 | 0.7 |
Positive | 5 (2.5) | 20 (9.9) | 25 (12.4) | ||