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Table 2 Correlation between MembErbB-2 prevalence detected by immunohistochemistry

From: Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer

Antibody

MembErbB-2, n(%)

Total N (%)

 

Negative

Positive

 

RBT-HER2

175 (87.1)

26 (12.9)

201

A0485

181(86.2)

29 (13.8)

210

C-18

177 (87.6)

25 (12.4)

202

  1. Because of the absence of some core sections on the slides, 201 patient samples could be analyzed for MembErbB-2 with RBT-HER2, 210 with A0485, and 202 with C-18. Scores of 3+ and only those of 2+ in which FISH confirmed ErbB-2 amplification were considered positive for MembErbB-2 overexpression