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Table 1 Studies on prognosis and XRCC1 Arg194Trp and Arg399Gln polymorphisms included in the meta-analysis

From: Association between polymorphisms in XRCC1 gene and clinical outcomes of patients with lung cancer: a meta-analysis

Study Year Country Ethnicity Case No. Stage Outcome SNPs
Gao et al. [24] 2006 China Asian 57 II-IV TR XRCC1 Arg194Trp and Arg399Gln
Ding et al. [25] 2010 China Asian 54 IIIB-IV TR XRCC1 Arg399Gln
Yuan et al. [26] 2006 China Asian 200 advanced TR XRCC1 Arg194Trp
Shi et al. [27] 2006 China Asian 112 II-IV TR XRCC1 Arg194Trp and Arg399Gln
Qiu et al. [28] 2009 China Asian 107 IIIA/B-IV TR XRCC1 T-77C and Arg194Trp
Sun et al. [18] 2009 China Asian 87 IV TR XRCC1 Arg194Trp and Arg399Gln
Song et al. [19] 2007 China Asian 97 IIIB-IV TR XRCC1 Arg194Trp and Arg399Gln
Wang et al. [20] 2004 China Asian 105 IIIB-IV TR XRCC1 Arg194Trp and Arg399Gln
Hong et al. [21] 2009 China Asian 164 III-IV TR XRCC1 Arg194Trp and Arg399Gln
Jin et al. [22] 2006 China Asian 162 IIIB-IV TR XRCC1 Arg194Trp
Qian et al. [23] 2010 China Asian 107 IIIA/B-IV TR XRCC1 Arg399Gln
Cheng et al. [29] 2011 China Asian 120 advanced TR XRCC1 Arg399Gln
Giachino et al. [30] 2007 Italy Caucasian 248 IIIA/B-IV TR/OS XRCC1 Arg399Gln
Butkiewicz et al. [31] 2010 Poland Caucasian 162 I, II or IIIA OS XRCC1 Arg399Gln
de las Penas R. et al. [32] 2006 Spain Caucasian 135 IIIB-IV OS XRCC1 Arg399Gln
Yin et al. [33] 2009 China Asian 257 I- IV OS XRCC1 Arg399Gln
Sreeja et al. [34] 2008 India Caucasian 211 I- IV OS XRCC1 Arg399Gln
Gurubhagavatula et al. [35] 2004 USA Caucasian 103 IIIA/B-IV OS XRCC1 Arg399Gln
Kalikaki et al. [36] 2009 Greece Caucasian 119 IIIA/B-IV TR/OS XRCC1 Arg399Gln
Liu et al. [37] 2008 China Asian 53 I- IV OS/PFS XRCC1 Arg399Gln
Han et al. [38] 2011 Korea Asian 158 IIIB-IV OS/PFS XRCC1 Arg399Gln
Yao et al. [39] 2009 China Asian 108 IIIA/B-IV OS XRCC1 Arg399Gln
  1. TR: objective response
  2. OS: overall survival
  3. PFS: progression-free survival