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Table 2 Expression of BCA2 and hHR23a in breast cancer cases

From: Effects of partner proteins on BCA2 RING ligase activity

  Cytoplasmic BCA2 Nuclear BCA2 Cytoplasmic hHR23a Nuclear hHR23a
Variable Low (%) High (%) P-value Low (%) High (%) P-value Low (%) High (%) P-value Low (%) High (%) P-value
ER                     
Positive 27 (34.2) 52 (65.8) 0.8053 29 (36.7) 50 (63.3) 0.4772 27 (34.2) 52 (65.8) *0.0181 39 (50.0) 39 (50.0) 0.4947
Negative 7 (29.2) 17 (70.8)   11 (45.8) 13 (54.2)   2 (8.3) 22 (91.7)   10 (41.7) 14 (58.3)  
PR                     
Positive 17 (31.3) 39 (68.7) 0.6743 17 (30.4) 39 (69.6) 0.0686 19 (33.9) 37 (66.1) 0.1897 26 (47.3) 29 (52.7) 1.000
Negative 17 (36.1) 30 (63.9)   23 (48.9) 24 (51.1)   10 (21.3) 37 (78.7)   23 (48.9) 24 (51.1)  
HER2                     
Positive 6 (35.3) 11 (64.7) 1.000 8 (47.1) 9 (52.9) 0.5878 5 (29.4) 12 (70.6) 1.000 10 (58.8) 7 (41.2) 0.4292
Negative 28 (32.9) 57 (67.1)   32 (37.6) 53 (62.4)   23 (27.1) 62 (72.9)   39 (46.4) 45 (53.6)  
Grade                     
1 2 (22.2) 7 (77.8) 0.5501 4 (44.4) 5 (55.6) * 0.0297 3 (33.3) 6 (66.7) 0.2730 5 (55.6) 4 (44.4) 0.4142
2 18 (38.3) 29 (61.7)   12 (25.5) 35 (74.5)   14 (29.8) 33 (70.2)   19 (41.3) 27 (58.7)  
3 14 (30.4) 32 (69.6)   24 (52.5) 22 (47.8)   12 (26.1) 34 (73.9)   25 (54.3) 21 (45.7)  
Nodal                     
Positive 11 (32.4) 23 (67.6) 1.000 10 (29.4) 24 (70.6) 0.1952 14 (41.2) 20 (58.8) 0.0585 17 (51.5) 16 (48.5) 0.6649
Negative 20 (33.3) 40 (66.7)   26 (43.3) 34 (56.7)   13 (21.7) 47 (78.3)   27 (45.0) 33 (55.0)  
  1. * Indicates a correlation which is statistically significant by Fisher's exact t-test or χ 2 test