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Table 3 Efficiency of α-type-1 DC production procedures

From: α-type-1 polarized dendritic cell-based vaccination in recurrent high-grade glioma: a phase I clinical trial

Case numbers

Starting total cell no. (×109 )

Optiprep (CD14+ %)

DC rate (%)* (lin-HLA-DR+)

Total DC numbers (×108 )

Recovery rate (%)

DC1/DC2 ratio

Il-12p70 level (pg/ml)

  

pre

post

     

9

6.50±3.4

11.9±9.4

44.6±21.8

56.1±19.0

4.22±1.7

8.79±5.1

35.6±39.6

1025±443

  1. * The frequency of DCs was determined from lineage (CD3, CD14, CD16, CD19, CD20, CD56)-HLA-DR+ cell population.