n |
TOX3mRNA
| p-value | n |
LOC643714mRNA
| p-value | ||
---|---|---|---|---|---|---|---|

139
| median (25% and 75%) |
126
| median (25% and 75%) | ||||

Age
| |||||||

< 50 | 59 (42%) | 1.92 (0.9 - 4.5) | 0.89 | 53 (42%) | 3.1 E-4 (5.6 E-6 - 1.5 E-2) | 0.07 | |

≥ 50 | 80 (58%) | 1.68 (1.1 - 4.0) | 73 (58%) | 1.7 E-3 (1.1 E-4 - 8.5 E-2) | |||

Tumour size (mm)
| |||||||

≤ 20 | 42 (31%) | 1.5 (1.0 - 4.8) | 0.45 | 39 (31%) | 6.4 E-4 (2.7 E-5 - 1.0 E-2) | 0.26 | |

> 20 | 95 (69%) | 2.0 (1.0 - 4.5) | 85 (69%) | 1.1 E-3 (9.2 E-5 - 8.5 E-2) | |||

unknown | 2 | 2 | |||||

Estrogen receptor
| |||||||

negative | 44 (33%) | 1.3 (0.4 - 3.3) | 0.004 | 41 (34%) | 9.3 E-6 (6.4 E-7 - 5.5 E-4) | < 0.001 | |

positive | 91 (67%) | 2.1 (1.1 - 4.5) | 81 (66%) | 2.4 E-3 (4.6 E-4 - 9.8 E-2) | |||

unknown | 4 | 4 | |||||

Progesterone receptor
| |||||||

negative | 65 (49%) | 1.4 (0.6 - 4.2) | 0.005 | 59 (50%) | 1.9 E-4 (1.4 E-6 - 3.1 E-3) | < 0.001 | |

positive | 67 (51%) | 2.1 (1.3 - 4.3) | 60 (50%) | 3.3 E-3 (4.2 E-4 - 0.5) | |||

unknown | 7 | 7 | |||||

ErbB2 status
| |||||||

negative | 114 (83%) | 1.8 (1.0 - 4.2) | 0.81 | 107 (86%) | 1.1 E-3 (6.6 E-5 - 7.7 E-2) | 0.04 | |

positive | 24 (17%) | 1.9 (0.8 - 5.0) | 18 (14%) | 2.7 E-4 (4.7 E-5 - 9.2 E-4) | |||

unknown | 1 | 1 | |||||

Nodal status
| |||||||

negative | 56 (44%) | 1.3 (0.4 - 3.4) | < 0.001 | 53 (46%) | 5.3 E-4 (1.9 E-6 - 2.3E-2) | 0.04 | |

positive | 71 (56%) | 2.2 (1.2 - 5.3) | 62 (54%) | 1.4 E-3 (2.0 E-4 - 5.7 E-2) | |||

unknown | 12 | 11 | |||||

Ki67
| |||||||

Low | 97 (71%) | 2.1 (1.1 - 4.4) | 0.026 | 87 (70%) | 2.4 E-3 (2.2 E-4 - 9.0 E-2) | < 0.001 | |

High | 39 (29%) | 1.2 (0.7 - 2.4) | 37 (30%) | 9.6 E-5 (1.9 E-6 - 9.0 E-4) | |||

unknown | 3 | 2 | |||||

Histograde
| |||||||

1 | 12 (9%) | 1.6 (0.8 - 3.5) | 0.16 | 12 (9%) | 1.1 E-3 (2.7 E-4 - 3.5 E-2) | 0.01 | |

2 | 78 (57%) | 1.9 (1.1 - 4.4) | 69 (56%) | 3.5 E-3 (1.9 E-4 - 9.8 E-2) | |||

3 | 47 (34%) | 1.6 (0.5 - 4.2) | 43 (35%) | 2.3 E-4 (3.3 E-6 - 1.5 E-3) | |||

unknown | 2 | 2 | |||||

Familial status
^{1}
| |||||||

BRCA2 | 26 (19%) | 2.9 (0.8 - 5.1) | 0.90 | 25 (20%) | 6.7 E-4 (1.2 E-4 - 4.2 E-3) | 0.40 | |

Non-BRCA2 | 112 (81%) | 1.6 (1.0 - 4.2) | 100 (80%) | 1.2 E-3 (6.3 E-5 - 6.4 E-2) | |||

unknown | 1 | 1 | |||||

Subtype
| |||||||

Basal | 20 (17%) | 0.5 (0.1 – 1.3) | < 0.001 | 23 (21%) | 3.1 E-6 (2.3 E-7 - 2.0 E-4) | < 0.001 | |

ERBB2 | 15 (12%) | 1.6 (1.2 - 5.0) | 9 (8%) | 9.7 E-4 (2.7 E-4 - 1.5 E-2) | |||

Luminal A | 43 (36%) | 1.6 (1.1 - 3.1) | 38 (35%) | 8.9 E-3 (5.0 E-4 - 9.8 E-2) | |||

Luminal B | 30 (25%) | 4.0 (1.6 - 5.4) | 28 (26%) | 1.2 E-3 (6.7 E-4 – 3.0 E-1) | |||

Normal-like | 12 (10%) | 1.8 (1.2 - 4.4) | 10 (9%) | 5.8 E-4 (3.4 E-5 - 2.7 E-3) | |||

Unclass/unknown | 19 | 18 | |||||

Histological type
| |||||||

Ductal | 116 (86%) | 2.1 (1.0 - 4.5) | 0.12 | 105 (86%) | 1.1 E-3 (9.2 E-5 - 5.2 E-2) | 0.91 | |

Lobular | 11 (8%) | 1.3 (1.3 - 2.2) | 9 (7%) | 6.2 E-4 (1.2 E-4 - 7.8 E-3) | |||

other | 8 (6%) | 1.0 (0.6 - 1.5) | 8 (7%) | 9.8 E-5 (5.2 E-6 - 2.2 E-2) | |||

unknown | 4 | 4 | |||||

Metastasis
| |||||||

negative | 63 (50%) | 1.6 (0.9 - 3.1) | 0.18 | 63 (55%) | 6.4 E-4 (6.3 E-6 - 1.9 E-2) | 0.16 | |

positive | 63 (50%) | 1.9 (1.1 - 4.9) | 52 (45%) | 1.6 E-3 (1.4 E-4 - 8.1 E-2) | |||

unknown | 13 | 11 |