Skip to main content

Table 6 Results of univariate analysis of survival after salvage chemoradiotherapy

From: Salvage chemoradiotherapy after primary chemotherapy for locally advanced pancreatic cancer: a single-institution retrospective analysis

  Factors No. of patients Median survival time (months) 6-month survival (%) 1-year survival (%) 2-year survival (%) p-value
All patients 30 8.8 77 33 26  
Age
  < 65 14 8.1 79 29 14  
  ≥ 65 16 9.2 75 38 38 0.2
Gender
  Male 16 8.1 75 31 25  
  Female 14 9.2 79 36 29 0.6
Karnofsky performance status
  ≥ 80 28 9.1 79 36 28  
  < 80 2 4.8 50 0 0 0.03
Primary tumor location
  Head 15 9.4 93 40 33  
  Body / tail 15 8.5 60 27 18 0.5
Number of regimens of primary chemotherapy
  1 25 9.4 80 40 32  
  2 5 6.1 60 0 0 0.006
Best response to primary chemotherapy
  PR 9 9.2 89 33 33  
  SD or PD 21 8.5 71 33 24 0.6
Pre-chemoradiotherapy tumor diameter (cm)
  ≤ 4 12 10.8 83 50 50  
  > 4 18 8.5 72 22 0 0.04
Pre-chemoradiotherapy serum CA19-9 level (U/ml)
  ≤ 1,000 29 10.8 90 47 42  
  > 1,000 11 6.4 54 9 0 0.002
Local progression before starting chemoradiotherapy
  Absent 4 NA 80 60 60  
  Present 26 8.8 76 28 19 0.15
Time from the start of primary chemotherapy to chemoradiotherapy  
  ≤ 6 months 12 8.5 75 33 25  
  > 6 months 18 8.8 78 33 28 0.9
Combined chemoradiotherapy agents
 5-FU 14 7.2 64 21 14  
 S-1 16 9.9 88 44 37 0.09
  1. PR partial response, SD stable disease, PD progressive disease, NA not available.