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Table 1 Characteristics of the 59 colorectal tumors included in the study data set

From: Molecular pathways undergoing dramatic transcriptomic changes during tumor development in the human colon

Preinvasive lesions
Patient Age Sex Colon segment Diameter (mm) Stage Histologic grade
Early stage (SPLs, diameters: 11–20 mm)
13b * 54 F Ascending 12 IIa TA (low)
21 66 M Ascending 12 IIa MVSP (none)
27 83 M Sigmoid 12 Ip TVA (low)
8 48 M Hepatic flexure 15 IIa TA (low)
15 62 F Ascending 15 IIa SA (low)
16 52 F Transverse 15 IIa SSA (none)
22 64 F Ascending 15 Ip TA (low)
23 56 M Ascending 15 Ip TA (low)
25 27 M Ascending 15 Ip TVA (high)
35 69 F Sigmoid 15 Ip TVA (low)
36 58 F Ascending 15 Ip TVA (low)
1b * 75 F Transverse 20 IIa VA (high)
2b * 72 F Transverse 20 IIa TA (low)
6 79 F Ascending 20 IIa TA (low)
7 67 F Ascending 20 IIa TA (low)
24 79 M Ascending 20 Ip TVA (low)
29 74 F Sigmoid 20 Ip TVA (low)
33 58 F Descending 20 Ip TA (low)
17b * 54 F Ascending 20 IIa TA (low)
Late-stage (LPLs, diameters: > 20 mm)
10 83 M Ascending 25 IIa TA (low)
11 66 M Cecum 25 IIa TA (high)
18 72 M Ascending 25 IIa TA (low)
19a * 79 M Ascending 25 IIa VA (low)
20 47 M Ascending 25 IIa-IIc MVSP (none)
2a * 72 F Cecum 30 IIa TA (low)
26 40 F Sigmoid 30 Ip TVA (low)
28 50 M Sigmoid 30 Ip TVA (high)
31 69 M Sigmoid 30 Ip TA (low)
32 56 M Sigmoid 30 Ip TA (low)
34 52 F Sigmoid 30 Ip TA (low)
19b * 79 M Transverse 30 Ip VA (low)
37 73 M Ascending 30 Ip TVA (high)
5 44 M Hepatic flexure 35 IIa TA (low)
12 79 M Ascending 35 IIa-IIc TVA (high)
3 75 F Transverse 40 IIa-IIc TA (high)
4 73 F Ascending 40 IIa-IIc SA (high)
9 69 F Ascending 40 IIa TVA (low)
30 69 M Rectum 40 Ip TA (low)
13a * 54 F Cecum 45 IIa TVA (low)
14 74 F Cecum 50 IIa TVA (low)
17a * 54 F Cecum 50 IIa TA (high)
1a * 75 F Transverse 70 IIa-IIb VA (high)
Invasive lesions (CRCs)
Patient Age Sex Colon segment Stage § Histologic grade §
38 58 F Ascending T3N0 G2
39 81 M Transverse T2N0 G2
40 61 M Sigmoid T3N1 G2
41 69 F Descending T4N2 G3
42 77 M Sigmoid T2N0 G2
43 67 M Sigmoid T3N2 G2
44 67 M Sigmoid T3N1 G2
45 57 M Sigmoid T3N0 G2
46 81 F Sigmoid T2N0 G2
47 77 M Descending T3N1 G2
48 73 F Cecum T3N1 G3
49 57 M Sigmoid T3N0 G2
50 55 M Descending T3N0 G2
51 90 F Cecum T3N0 G2
52 80 F Ascending T3N1 G2
53 75 F Ascending T3N0 G2
54 77 F Cecum T3N0 G2
  1. * Two lesions were analyzed from this patient.
  2. Paris Endoscopic Classification of Superficial Neoplastic Lesions (Gastrointest Endoscopy 2003;58[suppl.]:S3-S27).
  3. Preinvasive lesions were classified as tubular adenomas (TA), tubulovillous adenomas (TVA), villous adenomas (VA), microvescicular serrated polyps (MVSP), serrated adenomas (SA), sessile serrated adenomas (SSA). In parentheses, the degree of dysplasia (none, low, high) is reported based on the WHO classification of tumors of the digestive system (Editorial and consensus conference in Lyon, France, November 6–9, 1999 [IARC]).
  4. § Sobin LH, Wittekind C. TNM classification of malignant tumours. 6th ed. New York, NY: Wiley-Liss, 2002.