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Table 1 Characteristics of the 59 colorectal tumors included in the study data set

From: Molecular pathways undergoing dramatic transcriptomic changes during tumor development in the human colon

Preinvasive lesions

Patient

Age

Sex

Colon segment

Diameter (mm)

Stage

Histologic grade

Early stage (SPLs, diameters: 11–20 mm)

13b *

54

F

Ascending

12

IIa

TA (low)

21

66

M

Ascending

12

IIa

MVSP (none)

27

83

M

Sigmoid

12

Ip

TVA (low)

8

48

M

Hepatic flexure

15

IIa

TA (low)

15

62

F

Ascending

15

IIa

SA (low)

16

52

F

Transverse

15

IIa

SSA (none)

22

64

F

Ascending

15

Ip

TA (low)

23

56

M

Ascending

15

Ip

TA (low)

25

27

M

Ascending

15

Ip

TVA (high)

35

69

F

Sigmoid

15

Ip

TVA (low)

36

58

F

Ascending

15

Ip

TVA (low)

1b *

75

F

Transverse

20

IIa

VA (high)

2b *

72

F

Transverse

20

IIa

TA (low)

6

79

F

Ascending

20

IIa

TA (low)

7

67

F

Ascending

20

IIa

TA (low)

24

79

M

Ascending

20

Ip

TVA (low)

29

74

F

Sigmoid

20

Ip

TVA (low)

33

58

F

Descending

20

Ip

TA (low)

17b *

54

F

Ascending

20

IIa

TA (low)

Late-stage (LPLs, diameters: > 20 mm)

10

83

M

Ascending

25

IIa

TA (low)

11

66

M

Cecum

25

IIa

TA (high)

18

72

M

Ascending

25

IIa

TA (low)

19a *

79

M

Ascending

25

IIa

VA (low)

20

47

M

Ascending

25

IIa-IIc

MVSP (none)

2a *

72

F

Cecum

30

IIa

TA (low)

26

40

F

Sigmoid

30

Ip

TVA (low)

28

50

M

Sigmoid

30

Ip

TVA (high)

31

69

M

Sigmoid

30

Ip

TA (low)

32

56

M

Sigmoid

30

Ip

TA (low)

34

52

F

Sigmoid

30

Ip

TA (low)

19b *

79

M

Transverse

30

Ip

VA (low)

37

73

M

Ascending

30

Ip

TVA (high)

5

44

M

Hepatic flexure

35

IIa

TA (low)

12

79

M

Ascending

35

IIa-IIc

TVA (high)

3

75

F

Transverse

40

IIa-IIc

TA (high)

4

73

F

Ascending

40

IIa-IIc

SA (high)

9

69

F

Ascending

40

IIa

TVA (low)

30

69

M

Rectum

40

Ip

TA (low)

13a *

54

F

Cecum

45

IIa

TVA (low)

14

74

F

Cecum

50

IIa

TVA (low)

17a *

54

F

Cecum

50

IIa

TA (high)

1a *

75

F

Transverse

70

IIa-IIb

VA (high)

Invasive lesions (CRCs)

Patient

Age

Sex

Colon segment

Stage §

Histologic grade §

38

58

F

Ascending

T3N0

G2

39

81

M

Transverse

T2N0

G2

40

61

M

Sigmoid

T3N1

G2

41

69

F

Descending

T4N2

G3

42

77

M

Sigmoid

T2N0

G2

43

67

M

Sigmoid

T3N2

G2

44

67

M

Sigmoid

T3N1

G2

45

57

M

Sigmoid

T3N0

G2

46

81

F

Sigmoid

T2N0

G2

47

77

M

Descending

T3N1

G2

48

73

F

Cecum

T3N1

G3

49

57

M

Sigmoid

T3N0

G2

50

55

M

Descending

T3N0

G2

51

90

F

Cecum

T3N0

G2

52

80

F

Ascending

T3N1

G2

53

75

F

Ascending

T3N0

G2

54

77

F

Cecum

T3N0

G2

  1. * Two lesions were analyzed from this patient.
  2. Paris Endoscopic Classification of Superficial Neoplastic Lesions (Gastrointest Endoscopy 2003;58[suppl.]:S3-S27).
  3. Preinvasive lesions were classified as tubular adenomas (TA), tubulovillous adenomas (TVA), villous adenomas (VA), microvescicular serrated polyps (MVSP), serrated adenomas (SA), sessile serrated adenomas (SSA). In parentheses, the degree of dysplasia (none, low, high) is reported based on the WHO classification of tumors of the digestive system (Editorial and consensus conference in Lyon, France, November 6–9, 1999 [IARC]).
  4. § Sobin LH, Wittekind C. TNM classification of malignant tumours. 6th ed. New York, NY: Wiley-Liss, 2002.