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Table 2 Clinical-pathological prognostic features of disease

From: Detection methods predict differences in biology and survival in breast cancer patients

 

Incident (n = 65) vs. Symptomatic (n = 130)

P value

OR adjusted by tumor size

Mean age

59.7 ± 0.68 vs. 56.3 ± 1.14

p < 0.05

1.04 (1.01-1.08)

Mean size (cm)

1.27 ± 0.17 vs. 2.68 ± 0.15

p < 0.001

--

Lymph node positive

21.5% vs. 48.9%

p < 0.001

0.78 (0.34-1.76)

Poorly differentiated tumors

32.8 vs. 39.7%

N.S.

0.56 (0.27-1.17)

ER positive

89.1% vs. 57.4%

p < 0.001

4.23 (1.61-11.12)

PR positive

78.2 vs. 36.4%

p < 0.001

4.60 (2.11-10.03)

In situ carcinomas

11% vs. 1.5%

p < 0.001

2.44 (0.42-13.87)

Apoptosis

66.7% vs. 38.5%

p < 0.05

5.06 (1.71-14.94)

Bcl-2

81.3% vs. 62.7%

p < 0.05

1.39 (0.89-2.19)

c-erb-B2

26.3% vs. 23%

N.S.

0.86 (0.21-3.53)

Ki67

63% vs. 52.5%

N.S.

1.96 (0.93-4.09)

Delay Diagnosis- treatment (>30 days)

35.4% vs. 57%

p < 0.05

0.47 (0.23-0.95)