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Table 1 Clinical-pathological prognostic features of disease

From: Detection methods predict differences in biology and survival in breast cancer patients

 

Screen-detected (n = 161) vs. Symptomatic (n = 130)

P value

OR adjusted by tumor size

Mean age

56.33 ± 1.14 vs. 56.73 ± 1.18

N.S.

1.03 (0.99-1.05)

Mean size (cm)

1.62 + 0.14 vs. 2.68 + 0.15

p < 0.001

--

Lymph node positive

22.3% vs. 48.9%

p < 0.001

0.54 (0.31-0.95)

Poorly differentiated tumors

33.1% vs. 39.7%

N.S.

0.75 (0.47-1.20)

ER positive

87.8% vs. 57.4%

p < 0.001

4.76 (2.50-9.09)

PR positive

73.1% vs. 36.4%

p < 0.001

4.16 (2.43-7.14)

In situ carcinomas

11.4% vs.1.5%

p < 0.001

6.25 (1.35-33.3)

Apoptosis

48.8% vs. 38.5%

N.S.

1.53 (0.84-2.77)

Bcl-2

78.4% vs. 62.7%

p < 0.01

1.92 (1.08-3.44)

c-erb-B2

14.6% vs. 26.3%

p < 0.05

0.57 (0.15-0.97)

Ki67

46.7% vs. 52.5%

N.S.

0.97 (0.57-1.63)

Delay Diagnosis- treatment (>30 days)

47.5% vs. 57%

N.S.

0.75 (0.46-1.25)

  1. ER: estrogen receptor, PR: progesterone receptor.