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Table 4 Known activating EGFR mutations found in 152 patients (according to COSMIC database) a

From: Epidermal growth factor receptor (EGFR) mutations and expression in squamous cell carcinoma of the esophagus in central Asia

Origin of the patient Tehran India India India
Mutation type Missense Missense Missense Microdeletion
Exon No. 19 18 19 19
Nucleotide change c.2188C>T c.2156G>A c.2203C>T c.2235del15
Amino acid change p.L730F p.G719D p.P753L p.Q746_A750
  1. a http://www.sanger.ac.uk/genetics/CGP/cosmic/.