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Table 1 Androgen receptor (AR) expression and characteristics of breast cancer women in natural menopause

From: Androgen receptors and serum testosterone levels identify different subsets of postmenopausal breast cancers

 

AR expression

 
 

Absent

Poor

Moderate

High

 
 

No.

%b

No.

%b

No.

%b

No.

%b

P c

Age, yr

         

 < 65

29

49.2

55

49.1

57

47.5

68

42.5

0.259

 ≥ 65

30

50.8

57

50.9

63

52.5

92

57.5

BMI, kg/m2

         

 < 25

28

50.0

45

46.9

58

52.7

68

47.2

0.478

 25-30

18

32.1

41

42.7

34

30.9

44

30.6

 ≥ 30

10

17.9

10

10.4

18

16.4

32

22.2

Tumor size, cm

         

 < 2

32

55.2

74

66.7

70

58.8

112

70.9

0.080

 ≥ 2

26

44.8

37

33.3

49

41.2

46

29.1

Histology

         

 Infiltrating ductal carcinoma (IDC)

50

89.3

87

79.8

95

80.5

124

77.5

0.110

 Other infiltrating carcinoma

6

10.7

22

20.2

23

19.5

36

22.5

Grade

         

 ≤ 2

22

37.9

68

61.3

72

61.5

112

70.4

<0.001

 > 2

36

62.1

43

38.7

45

38.5

47

29.6

Axillary nodal status

         

 Negative

34

60.7

66

60.6

74

62.7

95

60.1

0.958

 Positive

22

39.3

43

39.4

44

37.3

63

39.9

ER status

         

 Negative

28

47.5

20

18.0

13

10.8

10

6.3

<0.001

 Positive

31

52.5

91

82.0

107

89.2

149

93.7

PR status

         

 Negative

34

57.6

42

38.2

37

30.8

36

22.6

<0.001

 Positive

25

42.4

68

61.8

83

69.2

123

77.4

HER2 statusa

         

 Negative

30

58.8

35

41.7

40

48.2

64

59.3

0.332

 Positive

21

41.2

49

58.3

43

51.8

44

40.7

Total

59

13.1 d

112

24.8 d

120

26.6 d

160

35.5 d

 
  1. NOTES. Androgen receptor (AR) expression: absent, 0%; poor, ≥1 to 30%; moderate, >30 to 60%; high, >60%. Estrogen receptor (ER)-positive and Progesterone receptor (PR)-positive: ER and PR expression ≥10%.
  2. aOne hundred and twenty-five (27.7%) women had missing information about HER2 status.
  3. bColumn percentage. cChi-square test for trend. dRow percentage.