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Table 4 Synergy and multiplicative indices between asbestos exposure and cigarette smoking

From: Occupational exposure to asbestos and lung cancer in men: evidence from a population-based case-control study in eight Canadian provinces

Cigarette smoking (pack-years)

Asbestos exposure

Label

Cases

Controls

Odds ratio*

95% CI

< 10

None

R0

84

745

1.0

-

 

Low

13

69

1.47

(0.77 – 2.81)

 

Medium/High

RA

2

7

2.20

0.42 – 11.41)

10 - < 40

None

630

778

5.28

(3.90 – 7.14)

 

Low

90

90

6.67

(4.41 – 10.10)

 

Medium/High

20

13

10.39

(4.83 – 22.36)

≥ 40

None

RS

678

266

17.68

(12.90 – 24.22)

 

Low

---

85

40

15.62

(9.72 – 25.09)

 

Medium/High

RAS

16

3

38.59

(10.78 – 138.08)

Synergy Index

    

2.10

 

Multiplicativity Index

    

0.99

 
  1. * adjusted for age, province, occupational exposure to diesel and silica, and second hand cigarette smoke.