Table 2 Univariate analysis of prognostic factors
Univariate analysis | n | % | 3-y-LC | p-value | 3-y-DC | p-value | 3-y-OS | p-value |
|---|---|---|---|---|---|---|---|---|
all patients | 97 | 100 | 52% | 48% | 52% | |||
age | ||||||||
< 60 yrs | 47 | 48 | 49% | 0.329 | 50% | 0.522 | 48% | 0.619 |
≥ 60 yrs | 50 | 52 | 55% | 47% | 55% | |||
gender | ||||||||
male | 59 | 61 | 44% | 0.023 | 52% | 0.779 | 53% | 0.701 |
female | 38 | 39 | 65% | 42% | 54% | |||
time FD to rec | ||||||||
< 30 mo | 48 | 49 | 49% | 0.308 | 46% | 0.389 | 43% | 0.398 |
≥ 30 mo | 49 | 51 | 55% | 50% | 61% | |||
T stage (FD)* | ||||||||
T1/2 | 34 | 35 | 64% | 0.13 | 61% | 0.056 | 70% | 0.045 |
T3/4 | 62 | 64 | 43% | 40% | 43% | |||
N stage (FD)* | ||||||||
N0 | 54 | 56 | 61% | 0.008 | 53% | 0.047 | 60% | 0.06 |
N+ | 41 | 42 | 39% | 42% | 37% | |||
UICC stage (FD)* | ||||||||
I/II | 53 | 55 | 60% | 0.015 | 55% | 0.03 | 62% | 0.046 |
III/IV | 42 | 43 | 41% | 41% | 41% | |||
resection margin | ||||||||
R0 | 36 | 37 | 82% | < 0.001 | 55% | 0.047 | 80% | < 0.001 |
R1 | 32 | 33 | 41% | 42% | 37% | |||
R2 | 29 | 30 | 18% | 48% | 35% | |||
EBRT | ||||||||
yes | 54 | 56 | 59% | 0.062 | 49% | 0.928 | 60% | 0.18 |
no | 43 | 44 | 41% | 50% | 43% | |||
EBRT | ||||||||
neoadj RT | 46 | 47 | 61% | 0.067 | 51% | 0.797 | 59% | 0.284 |
no RT | 43 | 44 | 41% | 50% | 43% | |||
adj. CHT | ||||||||
yes | 33 | 34 | 50% | 0.817 | 54% | 0.945 | 63% | 0.745 |
no | 64 | 66 | 54% | 47% | 45% | |||
resection of met | ||||||||
yes | 20 | 21 | 65% | 0.358 | 35% | 0.155 | 47% | 0.484 |
no | 77 | 79 | 49% | 52% | 54% | |||
local control achieved | ||||||||
yes | 52 | 54 | not amendable | 53% | 0.2 | 55% | 0.03 | |
no | 45 | 46 | 43% | 52% | ||||