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Table 2 Univariate analysis to identify prognostic factors for regional control

From: Neck control after definitive radiochemotherapy without planned neck dissection in node-positive head and neck cancers

Variable No. 3- year RC pvalue
Age (years)    0.146
   ≤ 60 32 84.4  
   > 60 18 61.9  
Gender    0.093
   Male 41 72.0  
   Female 9 100.0  
Primary site    0.22
   Nasopharynx 25 83.6  
   Non-Nasopharynx 25 72.0  
T classification    0.121
   1 14 68.8  
   2 19 84.2  
   3 8 100  
   4 9 55.6  
T classification    0.05
   1-3 41 82.0  
   4 9 55.6  
N classification    0.43
   1 12 91.7  
   2 30 71.9  
   3 8 75.0  
N classification    0.194
   1 12 91.7  
   2-3 38 72.7  
Initial maximal lymph node size (cm)    0.022
   ≤ 2 28 88.0  
   > 2 22 63.6  
RT modality    0.887
   Conventional 4 75  
   3D-CRT 25 73.8  
   IMRT 21 81.0  
Chemotherapy sequence    0.123
   Neoadjuvant + concurrent1 21 71.4  
   Concurrent + adjuvant2 17 94.1  
   Concurrent only 12 64.3  
Primary tumor response    < 0.001
   Complete response 38 88.1  
   Partial response 10 50.0  
   Progressive disease 2 0.0  
Primary tumor response    < 0.001
   Complete response 38 88.1  
   Non-complete response 12 41.7  
Residual maximal lymph node size (cm)    < 0.001
   ≤ 1.5 45 83.5  
   > 1.5 5 20.0  
Lymph node necrosis    < 0.001
   No 41 87.8  
   Yes 9 33.3  
Follow-up PET report    0.349
   Residual disease 4 50  
   Normal/Reactive change 27 78.1  
   Not available 19 78.9  
  1. RC: regional control
  2. 1. Two patients who received neoadjuvant chemotherapy only were included
  3. 2. Four patients who received additional one cycle of neoadjuvant chemotherapy were included