Neck control after definitive radiochemotherapy without planned neck dissection in node-positive head and neck cancers

Table 2 Univariate analysis to identify prognostic factors for regional control

Variable	No.	3- year RC	pvalue
Age (years)			0.146
≤ 60	32	84.4
> 60	18	61.9
Gender			0.093
Male	41	72.0
Female	9	100.0
Primary site			0.22
Nasopharynx	25	83.6
Non-Nasopharynx	25	72.0
T classification			0.121
1	14	68.8
2	19	84.2
3	8	100
4	9	55.6
T classification			0.05
1-3	41	82.0
4	9	55.6
N classification			0.43
1	12	91.7
2	30	71.9
3	8	75.0
N classification			0.194
1	12	91.7
2-3	38	72.7
Initial maximal lymph node size (cm)			0.022
≤ 2	28	88.0
> 2	22	63.6
RT modality			0.887
Conventional	4	75
3D-CRT	25	73.8
IMRT	21	81.0
Chemotherapy sequence			0.123
Neoadjuvant + concurrent¹	21	71.4
Concurrent + adjuvant²	17	94.1
Concurrent only	12	64.3
Primary tumor response			< 0.001
Complete response	38	88.1
Partial response	10	50.0
Progressive disease	2	0.0
Primary tumor response			< 0.001
Complete response	38	88.1
Non-complete response	12	41.7
Residual maximal lymph node size (cm)			< 0.001
≤ 1.5	45	83.5
> 1.5	5	20.0
Lymph node necrosis			< 0.001
No	41	87.8
Yes	9	33.3
Follow-up PET report			0.349
Residual disease	4	50
Normal/Reactive change	27	78.1
Not available	19	78.9

RC: regional control
1. Two patients who received neoadjuvant chemotherapy only were included
2. Four patients who received additional one cycle of neoadjuvant chemotherapy were included

ISSN: 1471-2407