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Table 5 Haplotypes of the three p21 SNPs in LD (rs1801270, rs3176352, and rs1059234) in patients and controls

From: Association of p21 SNPs and risk of cervical cancer among Chinese women

 

Patients

controls

  
 

(n=393)

(n=434)

  

haplotype

No. (%)

No. (%)

OR (95% CI)

P*a

ht1-AGT

    

ht1/ht1

67 (17.0)

87 (20.0)

0.643 (0.434-0.954)

0.028

ht1/-

166 (42.2)

215(49.5)

0.636 (0.467-0.865)

0.004

−/−

160(40.7)

132(30.4)

reference

 

ht2- CCC

    

ht2/ht2

26 (6.6)

41 (9.4)

0.628 (0.368-1.072)

0.088

ht2/-

183 (46.6)

210 (48.4)

0.865 (0.650-1.151)

0.321

−/−

184 (46.8)

183 (42.2)

reference

 

ht3-CGC

    

ht3/ht3

51 (13.0)

21 (4.8)

3.047 (1.788-5.192)

0.000

ht3/-

59 (15.0)

56 (12.9)

1.322 (0.888-1.970)

0.169

−/−

283 (72.0)

357 (82.3)

reference

 

ht4- CGT

    

ht4/ht4

3(0.8)

1(0.2)

3.054 (0.311-29.936)

0.338

ht4/-

50 (12.7)

32 (7.4)

1.846 (1.156-2.945)

0.010

−/−

340 (86.5)

401 (92.4)

reference

 
  1. * P value was adjusted for age and smoking by multiple logistic regressions.