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Table 3 Genotype frequencies for five p21 SNPs in cervical cancer patients and controls

From: Association of p21 SNPs and risk of cervical cancer among Chinese women

 

Patients

controls

  
 

(n=393)

(n=434)

  

SNP

No. (%)

No. (%)

OR (95% CI)

P*

rs762623

    

AA

9 (2.3)

16 (3.7)

0.627 (0.272-1.447)

0.274

AG

133 (33.8)

135 (31.1)

1.096(0.816-1.472)

0.542

GG

251 (63.9)

283 (65.2)

reference

 

rs2395655

    

AA

96 (24.4)

92 (21.2)

1.393 (0.936-2.074)

0.102

AG

207 (52.7)

222 (51.2)

1.245 (0.892-1.738)

0.197

GG

90 (22.9)

120 (27.6)

reference

 

rs1801270

    

AA

76 (19.3)

117 (27.0)

0.583(0.399-0.853)

0.005

AC

179 (45.5)

195 (44.9)

0.811 (0.590-1.114)

0.196

CC

138 (35.1)

110 (28.1)

reference

 

rs3176352

    

CC

37 (9.4)

56 (12.9)

0.637 (0.339-1.016)

0.058

CG

177 (45.0)

205 (47.2)

0.883 (0.623-1.114)

0.218

GG

179 (45.5)

173 (39.9)

reference

 

rs1059234

    

CC

131 (33.3)

102 (23.5)

1.392 (0.957-2.023)

0.083

CT

160 (40.7)

221 (50.9)

0.786 (0.560-1.101)

0.161

TT

102 (26.0)

111 (25.6)

reference

 
  1. * P value was adjusted for age and smoking by multiple logistic regressions. After Bonferroni correction, significant P value was <0.01.