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Table 3 Dose limiting toxic effects by dose level

From: Phase I study of imatinib, cisplatin and 5-fluoruracil or capecitabine in advanced esophageal and gastric adenocarcinoma

Dose level (mg)

n

Dose limiting toxicity (n)

300

6

nausea, anorexia (1)

400

3

-

500

3

-

600

11

-

700

2

gastric perforation (2)