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Table 2 Averaged PLA2R1 methylations in DNA from blood of normal individuals (Control, N = 52) and leukemic patients (Leukemia, N = 32) analysed by MS-HRM

From: Aberrant methylation of the M-type phospholipase A2 receptor gene in leukemic cells

Group N Methylation (mean ± SD)
Control 52 6.9% ± 2.5%
Leukemia 32 28.9% ± 17.8% **
  1. ** p = <0.001 in comparison to controls
  2. In the control group, one individual exhibited a PLA2R1 methylation of 21% and in the leukemic group, two patients had methylations of 7% and 3% (patient details see in Additional file 1: TableS1). The 95th percentile value usable as cut-off averaged 9%.