Figure 3
From: Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatin
Starvation sensitizes human mesothelioma xenografts to CDDP in vivo.. A, growth curves of ZL55 tumors in the untreated control animal group and those treated with CDDP, STS, or both together (n=5/group) (* P<0.05; ** P<0.01). B, complete tumor remission is observed only with the combined treatment. C, curves of average body weight of animals with ZL55 tumors in different groups during and after the treatments. Arrows in (A) and (C) indicate the time points of individual treatments.