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Table 2 Distribution of CYP2D6 alleles and genotypes

From: Reduced CYP2D6 function is associated with gefitinib-induced rash in patients with non-small cell lung cancer

Alleles Number
CYP2D6*1 236 (40.8%)
CYP2D6*2 63 (10.9%)
CYP2D6*10 211 (36.5%)
CYP2D6*14A 1 (0.2%)
Genotype Number
Functional  
CYP2D6*1/*1 67 (23.2%)
CYP2D6*1/*2 22 (7.6%)
CYP2D6*1/*10 72 (24.9%)
CYP2D6*1/*14A 1 (0.4%)
CYP2D6*1/undetermined 7 (2.4%)
CYP2D6*2/*2 9 (3.1%)
CYP2D6*2/*10 20 (6.9%)
CYP2D6*2/undetermined 3 (1.0%)
Total 201 (69.6%)
Reduced  
CYP2D6*10/*10 58 (20.1%)
Unknown  
CYP2D6*10/ undetermined 3 (1.0%)
undetermined/ undetermined 27 (9.3%)
Total 30 (10.3%)
  1. CYP2D6, cytochrome P450 2D6.