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Table 3 Predictive values for the QUANTEC guidelines and the developed NTCP models

From: Normal tissue complication probability model parameter estimation for xerostomia in head and neck cancer patients based on scintigraphy and quality of life assessments

Cut-off point (Gy) SEF QoL
PPV (%) NPV (%) PPV (%) NPV (%)
20-QUANTEC 19.2 100 23.1 100
25-QUANTEC 20.0 100 24.0 100
43.6-SEF-NTCP 50.0 92.0 45.5 95.0
44.1-QoL-NTCP 50.0 88.9 55.6 95.5
  1. Abbreviation: SEF salivary excretion factor, QoL quality of life, PPV positive predictive value, NPV negative predictive value, NTCP normal tissue complication probability, QUANTEC Quantitative Analyses of Normal Tissue Effects in the Clinic.