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Table 3 Predictive values for the QUANTEC guidelines and the developed NTCP models

From: Normal tissue complication probability model parameter estimation for xerostomia in head and neck cancer patients based on scintigraphy and quality of life assessments

Cut-off point (Gy)

SEF

QoL

PPV (%)

NPV (%)

PPV (%)

NPV (%)

20-QUANTEC

19.2

100

23.1

100

25-QUANTEC

20.0

100

24.0

100

43.6-SEF-NTCP

50.0

92.0

45.5

95.0

44.1-QoL-NTCP

50.0

88.9

55.6

95.5

  1. Abbreviation: SEF salivary excretion factor, QoL quality of life, PPV positive predictive value, NPV negative predictive value, NTCP normal tissue complication probability, QUANTEC Quantitative Analyses of Normal Tissue Effects in the Clinic.