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Table 3 Clinicopathological characteristics of node negative breast cancer patients (fresh frozen tissue) from the Transbig cohort (n=280)

From: Expression of aurora kinase A is associated with metastasis-free survival in node-negative breast cancer patients

Characteristics n %
Age at diagnosis   
<50 158 56.4
≥50 122 43.5
pT stage   
≤2cm 107 38.2
>2cm 173 61.8
Histological grade   
G I+II 165100 58.9
G III 15 35.7
not documented   5.4
Estrogen receptor   
RNA expression low 79 28.2
RNA expression high 201 71.8
Progesterone receptor   
RNA expression low 156 55.7
RNA expression high 124 43.3
Hormone receptor status1   
Negative   
Positive 78 27.9
  202 72.1
HER2 status   
RNA expression low 245 87.5
RNA expression high 35 12.5
Metastasis   
Yes 72 74.3
No 208 25.7
  1. Estrogen receptor, progesterone receptor and HER-2 status were derived from the gene array data. Cutpoints were 8.2 for the estrogen receptor, 10.2 for HER-2, and 4.5 for the progesterone receptor. Log2 transformed gene array data have been used.
  2. 1The hormone receptor status is positive when either the estrogen or progesterone receptor RNA expression is high.