Outcome | # studies | Pooled effect | Â | Â | Â | Test of heterogeneity | Â | Â |
---|---|---|---|---|---|---|---|---|
Physical outcomes | Â | d | 95% CI | Z | P | I2 | Q | P |
Physical function | 6 | 0.60 | −0.05 to 1.25 | 1.81 | 0.07 | 87.51 | 40.03 | <0.0001 |
 | 5a | 0.17 | −0.06 to 0.40 | 1.48 | 0.14 | 0.00 | 1.20 | 0.88 |
Functional well-being | 4 | 0.31 | 0.04 to 0.58 | 2.24 | 0.03 | 0.00 | 1.25 | 0.74 |
Psychosocial outcomes | Â | d | 95% CI | Z | P | I 2 | Q | P |
Distress | 7 | −0.95 | −1.49 to −0.49 | −4.04 | <0.001 | 80.79 | 31.24 | <0.001 |
 | 6b | −0.75 | −1.09 to −0.42 | −4.39 | <0.001 | 59.59 | 12.37 | 0.03 |
Anxiety | 7 | −1.25 | −1.93 to −0.56 | −3.64 | <0.001 | 91.45 | 70.20 | <0.001 |
 | 6b | −0.77 | −1.08 to −0.46 | −4.86 | <0.001 | 58.42 | 12.03 | 0.03 |
Depression | 7 | −1.47 | −2.42 to −0.53 | −3.05 | 0.002 | 93.29 | 89.46 | <0.001 |
 | 6b | −0.69 | −1.02 to −0.37 | −4.21 | <0.001 | 42.15 | 8.64 | 0.12 |
Fatigue | 7 | −0.51 | −0.79 to −0.22 | −3.46 | 0.001 | 43.52 | 10.62 | 0.10 |
Sleep disturbance | 4 | −0.26 | −0.53 to 0.02 | −1.82 | 0.07 | 0.00 | 1.25 | 0.74 |
General HRQoL | 7 | 0.88 | 0.25 to 1.50 | 2.75 | 0.006 | 86.49 | 44.41 | <0.001 |
 | 6a | 0.61 | 0.16 to 1.06 | 2.50 | 0.008 | 69.79 | 16.55 | 0.005 |
 | 5a,c | 0.37 | 0.11 to 0.62 | 2.85 | 0.004 | 0.00 | 3.40 | 0.49 |
Emotional function | 5 | 0.49 | 0.16 to 0.81 | 2.93 | 0.003 | 26.58 | 5.45 | 0.24 |
Social function | 6 | 0.33 | 0.12 to 0.54 | 3.12 | 0.002 | 0.00 | 1.94 | 0.86 |