Figure 6From: Salinomycin induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt Salinomycin induces phosphorylation of Akt. Western blotting shows an increase in phosphorylation of Akt (Ser473), as well as the immediate downstream targets GSK3-β (Ser9) and mTOR (Ser2448), when treated with the indicated doses of salinomycin. Total Erk is utilized as a loading control.Back to article page