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Table 1 Patient and breast cancer characteristics

From: A retrospective study investigating the rate of HER2 discordance between primary breast carcinoma and locoregional or metastatic disease

 

Study population

Ineligible population

p value

 

n=116

n=41

 
 

Number (%)

Number (%)

 

Age at diagnosis

   

  Median (yrs)

50

50

 

  Range

(31–85)

(34–73)

 

Year breast cancer diagnosis

   

  Pre - 2000

26 (22)

20 (49)

 

  2000–2001

19 (16)

6 (15)

0.01

  2002–2003

29 (25)

3 (8)

 

  2004–2005

21 (18)

9 (23)

 

  2006–2007

16 (14)

2 (5)

 

  2008-2009

5 (4)

1 (3)

 

Disease interval to biopsy (yrs)

   

  0 (metastatic at diagnosis)

9 (8)

5 (12)

 

  0.5 – 2y

29 (25)

2 (5)

0.02

  2.1 – 5

44 (38)

14 (34)

 

  >5y

34 (29)

20 (49)

 

Type of biopsy

   

  Local recurrence site

40 (34)

7 (17)

0.05

  Distant recurrence site

76 (66)

34 (83)

 

Site of recurrent or metastatic biopsy

   

  Breast

24 (20)

3 (7)

 

  Lymph nodes

20 (17)

10 (24)

 

  Chest wall / Skin

18 (16)

4 (10)

0.13

  Bone

14 (12)

9 (22)

 

  Liver

9 (8)

5 (12)

 

  Brain

9 (8)

2 (5)

 

  Lung

7 (6)

0

 

  Others

15 (13)

8 (20)

 

Type of tissue biopsy

   

  Fine needle aspiration

34 (29)

13 (32)

0.84

  Core / Excisional biopsy

82 (71)

28 (68)