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Open Access
Open Peer Review

This article has Open Peer Review reports available.

How does Open Peer Review work?

Gonadotropin-releasing hormone receptor activates GTPase RhoA and inhibits cell invasion in the breast cancer cell line MDA-MB-231

  • Arturo Aguilar-Rojas1, 2Email author,
  • Maira Huerta-Reyes1,
  • Guadalupe Maya-Núñez2,
  • Fabián Arechavaleta-Velásco2,
  • P Michael Conn3,
  • Alfredo Ulloa-Aguirre4 and
  • Jesús Valdés5
BMC Cancer201212:550

Received: 18 June 2012

Accepted: 25 October 2012

Published: 23 November 2012

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
18 Jun 2012 Submitted Original manuscript
10 Sep 2012 Reviewed Reviewer Report - Patrizia Limonta
25 Sep 2012 Reviewed Reviewer Report - Simon Langdon
16 Oct 2012 Author responded Author comments - Arturo Aguilar-Rojas
Resubmission - Version 2
16 Oct 2012 Submitted Manuscript version 2
25 Oct 2012 Editorially accepted
23 Nov 2012 Article published 10.1186/1471-2407-12-550

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

Centro de Investigación Biomédica del Sur (CIBIS), Instituto Mexicano del Seguro Social (IMSS)
Research Unit in Reproductive Medicine, Unidad Médica de Alta Especialidad-Hospital de Ginecobstetricia No. 4 “Luis Castelazo Ayala” IMSS
Oregon National Primate Research Center, Oregon Health Sciences University
Division of Reproductive Health, Research Center in Population Health, National Institute of Public Health
Departament of Biochemistry, Centro de Investigación y de Estudios Avanzados (CINVESTAV)