Table 1 Median and range of adiponectin, resistin, leptin, active PAI-1, MCP-1, IL-1α and TNF-α plasma concentrations of patients operated on for colorectal carcinoma (CRC) and morbid obesity (MO) as well as healthy blood donors (BD)

Adiponectin (μg/ml)

17.1

↓9.4

14.7

n.s.

p<0.001

p<0.001

3.9 / 7.8

(4.3 – 51.0)

(3.8 – 57.8)

(5.7 – 54.0)

Adiponectin females (μg/ml)

21.9

↓12.4

22.5

n.s.

p<0.001

p=0.002

(7.0 – 40.5)

(5.3 – 57.8)

(9.8 – 54.0)

Adiponectin males (μg/ml)

14.2

↓8.3

11.8

n.s.

p=0.001

p<0.001

(4.3 – 51.0)

(3.8 – 12.3)

(5.7 – 30.7)

Leptin (ng/ml)

↓2.6

↑45.0

10.9

p<0.001

p<0.001

p<0.001

6.4 / 9.6

(0.3 – 33.3)

(1.7 – 97.5)

(0.3 – 58.5)

Leptin females

↓6.7

↑47.3

15.8

p=0.011

p<0.001

p<0.001

(0.3 - 33.3)

(16.1 – 97.5)

(0.7 – 58.5)

Leptin males

↓1.7

↑34.2

4.7

p=0.001

p<0.001

p<0.001

(0.3 – 19.6)

(1.7 – 90.9)

(0.3 – 19.1)

Resistin (ng/ml)

10.9

9.9

10.8

n.s.

n.s.

n.s.

8.3 / 11.1

(4.2 – 43.5)

( 3.7 – 83.6)

(5.2 – 24.9)

MCP-1 (pg/ml)

↑127

↑108

43.9

p<0.001

p<0.001

p=0.047

5.1 / 11.2

(22.7 – 451)

(39.6 – 293)

(12.1 – 150)

Active PAI-1 (ng/ml)

↑13.2

↑57.5

6.0

p<0.001

p<0.001

p<0.001

17.4 / 20.0

(2.4 – 53.2)

(3.7 – 176.7)

( 2.4 – 31.3)

TNF-α(pg/ml)

4.8 (n=63)

4.0

3.9

n.s.

n.s.

n.s.

9.4 / 10.7

(2.4 – 74.7)

(2.4 – 26.8)

( 2.4 – 10.9)

IL-1α (pg/ml)

↑52.4 (n=63)

↑59.4

11.0

p<0.001

p<0.001

n.s.

20.0 / 35.7

(9.2 – 1322)

(9.2 – 210.0)

( 9.2 – 168)