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Table 1 Median and range of adiponectin, resistin, leptin, active PAI-1, MCP-1, IL-1α and TNF-α plasma concentrations of patients operated on for colorectal carcinoma (CRC) and morbid obesity (MO) as well as healthy blood donors (BD)

From: Changed adipocytokine concentrations in colorectal tumor patients and morbidly obese patients compared to healthy controls

Parameters Intra-CV% Inter-CV% CRC (n=67) MO (n=37) BD (n=60) CRC vs. BD MO vs. BD CRC vs. MO
Adiponectin (μg/ml) 17.1 9.4 14.7 n.s. p<0.001 p<0.001
3.9 / 7.8 (4.3 – 51.0) (3.8 – 57.8) (5.7 – 54.0)
Adiponectin females (μg/ml) 21.9 12.4 22.5 n.s. p<0.001 p=0.002
(7.0 – 40.5) (5.3 – 57.8) (9.8 – 54.0)
Adiponectin males (μg/ml) 14.2 8.3 11.8 n.s. p=0.001 p<0.001
(4.3 – 51.0) (3.8 – 12.3) (5.7 – 30.7)
Leptin (ng/ml) 2.6 45.0 10.9 p<0.001 p<0.001 p<0.001
6.4 / 9.6 (0.3 – 33.3) (1.7 – 97.5) (0.3 – 58.5)
Leptin females 6.7 47.3 15.8 p=0.011 p<0.001 p<0.001
(0.3 - 33.3) (16.1 – 97.5) (0.7 – 58.5)
Leptin males 1.7 34.2 4.7 p=0.001 p<0.001 p<0.001
(0.3 – 19.6) (1.7 – 90.9) (0.3 – 19.1)
Resistin (ng/ml) 10.9 9.9 10.8 n.s. n.s. n.s.
8.3 / 11.1 (4.2 – 43.5) ( 3.7 – 83.6) (5.2 – 24.9)
MCP-1 (pg/ml) 127 108 43.9 p<0.001 p<0.001 p=0.047
5.1 / 11.2 (22.7 – 451) (39.6 – 293) (12.1 – 150)
Active PAI-1 (ng/ml) 13.2 57.5 6.0 p<0.001 p<0.001 p<0.001
17.4 / 20.0 (2.4 – 53.2) (3.7 – 176.7) ( 2.4 – 31.3)
TNF-α(pg/ml) 4.8 (n=63) 4.0 3.9 n.s. n.s. n.s.
9.4 / 10.7 (2.4 – 74.7) (2.4 – 26.8) ( 2.4 – 10.9)
IL-1α (pg/ml) 52.4 (n=63) 59.4 11.0 p<0.001 p<0.001 n.s.
20.0 / 35.7 (9.2 – 1322) (9.2 – 210.0) ( 9.2 – 168)
  1. ↓↑: Significantly elevated/lowered concentrations compared to BD.The inter- and intra-assay CVs are given below the corresponding parameters.