Leptin concentrations of CRC patients according to tumor localization (colon cancer vs. rectal cancer). Male colon cancer patients had (not significant) elevated leptin concentrations compared to male rectal cancer patients (median colon cancer leptin: 1.7 ng/ml; range: 0.3 – 19.6 ng/ml vs. median rectal cancer leptin: 0.8 ng/ml; range: 0.3 – 6.7 ng/ml; p=0.062). There was no difference in female patients (leptin: 9.2 ng/ml; range: 0.3 – 30.8 ng/ml vs. median rectal cancer leptin: 6.3 ng/ml; range: 0.3 – 33.3 ng/ml; p=0.07). The top and bottom of the rectangle represent the 25th and 75th percentile. The line within the rectangle represents the median. The whiskers extend from the 5th percentile to the 95th percentile.