Figure 6

PTEN deletion is associated with low AR expression in an independent PCa cohort. PTEN deletion status as determined by array CGH was associated with low AR mRNA levels as measured by gene expression profiling of 64 PCa cases from the dataset of Lapointe et al. The box-plot shows the mean (+ sign), the 25th, 50th (median), 75th percentiles of AR expression including the minimum and maximum (unequal variance t-test, P-value indicated). Values are reported as log₂ ratios, normalized to the sample-set mean.