Figure 1

Mcl-1 and Bcl-xL are co-overexpressed in multiple solid tumor types. (a) Mcl-1 and Bcl-xL expression patterns in lung and colon adenocarcinomas. The co-existence of Mcl-1 and Bcl-xL expression in tumor cells on the tissue slides was assessed using the Fisher exact and Chi-square tests. (b) The association between Bcl-xL or Mcl-1 expression and clinical staging in colon cancer samples was measured using linear regression. Protein expression levels between stages were compared using pre-planned contrasts. The mean levels within each stage, plus or minus one standard error, are plotted.