Aberrant expression of CD133 in non-small cell lung cancer and its relationship to vasculogenic mimicry

BMC Cancer

Table 1 Correlation of CD133 expression and VM to clinicopathological characteristics in NSCLC

Variable	CD133		P value	VM		P value	MVD		P value
Variable	Negative	Positive	P value	Negative	Positive	P value	(mean)	F	P value
Tissue			<0.05			<0.001
Normal	22	8		0	30
NSCLC	156	149		196	109
Gender			>0.05			>0.05		0.154	>0.05
Male	117	116		150	83		22.2±11.3
Female	39	33		46	26		21.6±10.9
Ages			>0.05			>0.05		0.476	>0.05
<60	77	64		93	48		21.5±11.8
≥60	79	85		103	61		22.4±10.7
Gross type			>0.05			>0.05		0.004	>0.05
Central	114	110		141	83		22.0±11.6
Peripheral	42	39		55	26		21.9±10.1
Histological type			>0.05			>0.05		3.550	>0.05
Squamous carcinoma	111	99		141	69		21.2±11.3
Adenocarcinoma	45	50		55	40		23.8±10.7
Diameter of tumor			>0.05			>0.05		0.133	>0.05
<3.0cm	13	17		20	10		21.3±11.1
≥3.0cm	143	132		176	99		22.1±11.2
Differentiation			<0.001			<0.001		31.231	<0.001
Well	30	4		32	2		13.6±7.1
Moderate	104	99		142	61		20.9±9.7
Poor	22	46		22	46		29.6±12.9
Lymph node metastasis			<0.001			<0.001		67.650	<0.001
Yes	71	114		93	92		25.9±10.2
No	85	35		103	17		16.1±10.0
pTNM stage			<0.001			<0.001		200.694	<0.001
Iand II	111	29		129	11		14.3±6.7
III and IV	45	120		67	98		28.5±10.1
VM			<0.001					471.458	<0.001
Negative	143	53					15.5±5.9
Positive	13	96					33.7±8.7
CD133						<0.001		216.747	<0.001
Negative				143	13		15.0±7.2
Positive				53	96		29.4±9.8

ISSN: 1471-2407