Skip to main content

Table 4 Comparison of the expected cases ( E ) of invasive breast cancer predicted by each respective model, to the observed cases ( O ) in the Singapore Breast Screening Programme (SBSP) cohort by risk factor category

From: Assessing risk of breast cancer in an ethnically South-East Asia population (results of a multiple ethnic groups study)

Risk factors

No. of women followed

  

GAIL-SBSP

  

S-GAIL-SBSP

  

E-GAIL-SBSP

 
  

O

E

E/O(CI)

P

E

E/O(CI)

P

E

E/O(CI)

P

AGEMEN (y)

           

 ≥14

18,652

142

148.50

1.05 (0.89 to 1.23)

0.890

139.32

0.98 (0.83 to 1.16)

0.945

165.22

1.16 (0.99 to 1.37)

0.035

 12–13

9,279

89

83.81

0.94 (0.77 to 1.16)

 

90.61

1.02 (0.83 to 1.25)

 

109.59

1.23 (1.00 to 1.52)

 

 <12

952

10

9.53

0.95 (0.51 to 1.77)

 

11.87

1.19 (0.64 to 2.21)

 

14.66

1.47 (0.79 to 2.73)

 

NBIOPS

           

 0

27,176

218

222.80

1.02 (0.89 to 1.17)

0.629

226.43

1.04 (0.91 to 1.19)

0.129

271.38

1.24 (1.09 to 1.42)

0.003

 1

1,707

23

19.04

0.83 (0.55 to 1.25)

 

15.37

0.67 (0.44 to 1.01)

 

18.09

0.79 (0.52 to 1.18)

 

NUMREL

           

 0

28,143

225

229.50

1.02 (0.90 to 1.16)

0.045

227.71

1.01 (0.89 to 1.15)

0.109

272.98

1.21 (1.06 to 1.38)

0.004

 1

729

14

11.98

0.86 (0.51 to 1.44)

 

13.67

0.98 (0.58 to 1.65)

 

16.01

1.14 (0.68 to 1.93)

 

 ≥2

11

2

0.36

0.18 (0.04 to 0.71)

 

0.42

0.21 (0.05 to 0.83)

 

0.48

0.24 (0.06 to 0.97)

 

AGEFLB (y)

           

 <20

4,952

26

29.89

1.15 (0.78 to 1.69)

0.900

31.58

1.21 (0.83 to 1.78)

0.750

39.77

1.53 (1.04 to 2.25)

0.038

 20–24

10,840

77

80.61

1.05 (0.84 to 1.31)

 

81.02

1.05 (0.84 to 1.32)

 

94.41

1.23 (0.98 to 1.53)

 

 25–29 or nulliparous

9,843

97

93.48

0.96 (0.79 to 1.18)

 

92.61

0.95 (0.78 to 1.16)

 

112.39

1.16 (0.95 to 1.41)

 

 ≥30

3,248

41

37.85

0.92 (0.68 to 1.25)

 

36.59

0.89 (0.66 to 1.21)

 

42.90

1.05 (0.77 to 1.42)

 

BMI (kg/m2)

           

 <23.0

10,237

68

89.31

1.31 (1.04 to 1.67)

0.018

88.34

1.30 (1.02 to 1.65)

0.028

75.94

1.12 (0.88 to 1.42)

0.026

 23.0–27.4

12,225

107

101.99

0.95 (0.79 to 1.15)

 

102.09

0.95 (0.79 to 1.15)

 

124.26

1.16 (0.96 to 1.40)

 

 ≥27.5

6,411

66

50.45

0.76 (0.60 to 0.970

 

51.29

0.78 (0.61 to 0.99)

 

89.21

1.35 (1.06 to 1.72)

 

Parity

           

 ≥3

20,197

147

156.72

1.07 (0.91 to 1.25)

0.632

157.01

1.07 (0.91 to 1.26)

0.615

178.11

1.21 (1.03 to 1.42)

0.041

 1–2

6,410

68

63.16

0.93 (0.73 to 1.18)

 

62.80

0.92 (0.73 to 1.17)

 

78.57

1.16 (0.91 to 1.47)

 

 0

2,276

26

21.95

0.84 (0.57 to 1.24)

 

21.99

0.85 (0.58 to 1.24)

 

32.78

1.26 (0.86 to 1.85)

 
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us