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Table 4 Cellular functions of selected genes that are differentially expressed in GC specimens that overexpress Snail

From: Overexpression of Snail is associated with lymph node metastasis and poor prognosis in patients with gastric cancer

Probe ID

Gene acronym

Gene name

Accession No.

Pvalue

Cancer cell–ECM adhesion

ILMN_1759487

EGFLAM

EGF-like, fibronectin type III, and laminin G domains (↑)

NM_182801

0.005

ILMN_2114812

ONECUT1

One cut homeobox 1 (↓)

NM_004498

0.002

ILMN_2374449

SPP1

Secreted phosphoprotein 1 (↑)

NM_000582

0.004

ECM protein regulation

ILMN_1676452

ADAMTS14

ADAM metallopeptidase with thrombospondin type 1 motif, 14 (↑)

NM_080722

0.005

ILMN_1759487

EGFLAM

EGF-like, fibronectin type III, and laminin G domains (↑)

NM_182801

0.005

ILMN_1683453

FRAS1

Fraser syndrome 1 (↓)

NM_020875

0.003

ILMN_1791057

IFNAR2

Interferon (alpha, beta, and omega) receptor 2 (↑)

NM_207585

0.001

ILMN_1756455

IL5RA

Interleukin 5 receptor, alpha (↓)

NM_000564

0.004

ILMN_1747850

CRIM2

Kielin/chordin-like protein (↑)

NM_199349

0.005

ILMN_1743301

MSR1

macrophage scavenger receptor 1 (↓)

NM_002445

0.002

ILMN_2374449

SPP1

secreted phosphoprotein 1 (↑)

NM_000582

0.004

ILMN_2256050

SERPINA1

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (↑)

NM_000295

0.002

ILMN_2060115, ILMN_1759818

SORL1

Sortilin-related receptor, L(DLR class) A repeats-containing (↑)

NM_003105

0.003 <0.001

  1. NOTE: ↑, upregulation; ↓, downregulation.