Table 1 Univariate analyses of uPA and PAI-1 expression (ng/mL) in women requiring breast surgery

All Subjects (N)

79

46

33

uPA

Mean (SD)

2.4 (.90)

2.2 (.84)

2.7 (.92)

.023

Median

2.4

2.2

2.6

PAI-1

Mean (SD)

3.7 (1.5)

3.4 (1.4)

4.2 (1.6)

.064

Median

3.5

3.3

4.1

Premenopausal (N)

38

23

15

uPA

Mean (SD)

2.5 (.93)

2.2 (.82)

2.9 (.93)

.018

Median

2.5

2.3

2.7

Postmenopausal (N)

41

23

18

PAI-1

Mean (SD)

4.0 (1.6)

3.5 (1.6)

4.6 (1.4)

.025

Median

3.8

3.3

4.3

B. Cancer/benign

Overall

Benign ¹

Cancer ¹

P value

All Subjects (N)

72

39

33

uPA

Mean (SD)

2.4 (.93)

2.2 (.89)

2.7 (.92)

.025

Median

2.4

2.2

2.6

PAI-1

Mean (SD)

3.7 (1.5)

3.4 (1.4)

4.2 (1.6)

.037

Median

3.4

3.1

4.1

Premenopausal (N)

37

22

15

uPA

Mean (SD)

2.4 (.95)

2.2 (.84)

2.9 (.93)

.017

Median

2.5

2.2

2.7

Postmenopausal (N)

35

17

18

PAI-1

Mean (SD)

4.0 (1.7)

3.4 (1.7)

4.6 (1.4)

.033

Median

3.8

2.8

4.3

C. Abnormal/benign

Overall

Benign ¹

Abnormal ¹

P value

All Subjects (N)

79

39

40

uPA

Mean (SD)

2.4 (.90)

2.2 (.89)

2.6 (.88)

.050

Median

2.4

2.2

2.5

PAI-1

Mean (SD)

3.7 (1.5)

3.4 (1.4)

4.0 (1.6)

.060

Median

3.5

3.1

3.9

Premenopausal (N)

38

22

16

uPA

Mean (SD)

2.5 (.93)

2.2 (.84)

2.9 (.91)

.018

Median

2.5

2.2

2.7

Postmenopausal (N)

41

17

24

PAI-1

Mean (SD)

4.0 (1.6)

3.4 (1.7)

4.4 (1.3)

.052

Median

3.8

2.8

4.1