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Table 6 GASC1 and survival of breast cancer patients according to the type of adjuvant treatment

From: Histone demethylase GASC1 - a potential prognostic and predictive marker in invasive breast cancer

Cases n RFS BCSS OS
   HR 95% CI p* HR 95% CI p* HR 95% CI p*
radiotherapy 206          
negative 119       
positive 87 0.52 0.33 to 0.83 0.006 0.49 0.29 to 0.82 0.007 0.71 0.47 to 1.06 0.097
tamoxifen 62          
negative 25 1†    1†    1†   
positive 37 0.45 0.21 to 0.99 0.048 0.33 0.13 to 0.81 0.015 0.66 0.34 to 1.29 0.23
chemotherapy 69          
negative 43 1‡    1‡    1‡   
positive 26 0.64 0.29 to 1.38 0.25 0.70 0.30 to 1.64 0.41 0.81 0.36 to 1.82 0.60
  1. RFS = relapse-free survival; BCSS = breast cancer specific survival; OS = overall survival.
  2. *p was based on Cox proportional analysis.
  3. §Reference value; HRs adjusted for age and stage at diagnosis, chemotherapy, hormonal treatment and hormone receptor status.
  4. †Reference value; HRs adjusted for age and stage at diagnosis and radiotherapy.
  5. ‡Reference value; HRs adjusted for age and stage at diagnosis, radiotherapy and hormone receptor status.