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Table 4 GASC1 immunostaining according to histopathological and molecular parameters

From: Histone demethylase GASC1 - a potential prognostic and predictive marker in invasive breast cancer

Variable n GASC1 negative n (%) GASC1 positive n (%) p-value, chi2
Number of patients 355 198 (55.8) 157 (44.2)  
Histological type     
 Ductal 231 143 (62) 88 (38) 0.005
 Lobular 66 31 (47) 35 (53)  
 Rare 58 24 (41) 34 (59)  
Histological grade     
 I 84 31 (37) 53 (63) 0.000
 II 166 84 (51) 82 (49)  
 III 103 81 (79) 22 (21)  
 unknown 2    
ER status     
 negative 77 51 (66) 26 (34) 0.033
 positive 272 143 (53) 129 (47)  
 unknown 6    
PR status     
 negative 137 91 (66) 46 (34) 0.001
 positive 212 103 (49) 109 (51)  
 unknown 6    
HER2 status     
 negative 290 156 (54) 134 (46) 0.029
 positive 45 32 (71) 13 (29)  
 unknown 20    
  1. n – number of cases.