Table 4 GASC1 immunostaining according to histopathological and molecular parameters
From: Histone demethylase GASC1 - a potential prognostic and predictive marker in invasive breast cancer
Variable | n | GASC1 negative n (%) | GASC1 positive n (%) | p-value, chi2 |
|---|---|---|---|---|
Number of patients | 355 | 198 (55.8) | 157 (44.2) | Â |
Histological type | Â | Â | Â | Â |
 Ductal | 231 | 143 (62) | 88 (38) | 0.005 |
 Lobular | 66 | 31 (47) | 35 (53) |  |
 Rare | 58 | 24 (41) | 34 (59) |  |
Histological grade | Â | Â | Â | Â |
 I | 84 | 31 (37) | 53 (63) | 0.000 |
 II | 166 | 84 (51) | 82 (49) |  |
 III | 103 | 81 (79) | 22 (21) |  |
 unknown | 2 |  |  |  |
ER status | Â | Â | Â | Â |
 negative | 77 | 51 (66) | 26 (34) | 0.033 |
 positive | 272 | 143 (53) | 129 (47) |  |
 unknown | 6 |  |  |  |
PR status | Â | Â | Â | Â |
 negative | 137 | 91 (66) | 46 (34) | 0.001 |
 positive | 212 | 103 (49) | 109 (51) |  |
 unknown | 6 |  |  |  |
HER2 status | Â | Â | Â | Â |
 negative | 290 | 156 (54) | 134 (46) | 0.029 |
 positive | 45 | 32 (71) | 13 (29) |  |
 unknown | 20 |  |  |  |