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Table 3 Time to relapse by Kaplan-Meier analysis

From: Histone demethylase GASC1 - a potential prognostic and predictive marker in invasive breast cancer

Variable

n

Means of survival time (years) / n

p-value, Log Rank

  

GASC1 negative

GASC1 positive

 

Overall

355

12.9/198

14.8/157

0.034 (0.005B, 0.010T-W)

Age

    

 <=55

172

12.9/107

14.9/65

0.168

 >55

183

12.9/ 91

14.5/92

0.098, (0.035 B, 0.052 T-W)

Tumor size

    

 T1

168

14.8/ 92

15.6/76

0.331

 T2+T3+T4

187

11.1/106

13.9/81

0.040 (0.013B, 0.018 T-W)

Nodal status

    

 negative

193

15.5/111

16.6/82

0.135

 positive

162

9.1/ 87

12.8/75

0.013 (0.002B, 0.004 T-W)

Clinical stage

    

 I

120

16.2/ 66

16.5/ 54

0.580

 II+III+IV

230

11.1/130

14.0/100

0.014 (0.003 B, 0.005 T-W)

  1. p-value for test of equality of survival distributions for the different levels of GASC1, B: Breslow (Generalized Wilcoxon),T-W: Tarone –Ware, n – number of cases.