Table 1 Putative small molecule binding sites in EWS-FLI1 protein

4

21,156–167,170,173,176-196,203-207,218- 223 247,248, 317–327, 389, 391, 394,447-450,454,498

1.151

3

109-112,117,120,121,124,125,128,129,146-148,150-153,298 305, 307, 308,310,315,317,324,325,327,328,331,332,335,345,347,380,382,383,385-389, 481-490

1.077

2

12-16,54-64,66-69,81-86,89-98,100-103,105,107,109,112,119 – 124, 127 , 128,132-146,272,276,290,296,311

1.047

6

25,65,71-75,77,209,213-217,236-247,250,254-264,278-286

1.043

5

1,14-16,29,31,32,35,36,41-44,49,50,54-59,66,67,90,92-97,261-264,267-272

1.032

9

150,151,158-160,315,317-329,350,377-380,387-391,456,461,489-492

1.026

1

22,25-34,36-40,163,188,190-211,214,216-218,246-254,257-259, 261,262,264,279-282,318,352,365-369,377,378,391-401,436,439-450,454

1.007

8

179-181,184,206-208,216,219-223,229-237,240,244,246,285,288,289

0.944

7

11,104,106,144-147,307-314,374,383-388,410-413,476,479-482,484

0.948

10

61-63,80-86,89,118,119,223,234,235,288-296

0.777