Figure 4

Diversity of sbsRT in healthy and cancer cells. SBS were tracked for 8,572 RT in 7 healthy (circles) and 8 cancer (triangles) Tag-seq experiments. The 8,572 RT were distributed into sequence diversity groups according to the number of distinct sbsRT sequences. For example, group 0, i.e. RT for which 0 sbsRT were observed, contained approximately 350 RT in cancer and slightly more than 800 RT in healthy cells. RT associated with more than 30 distinct sbsRT were rare.