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Table 6 Association of organic solvent exposure with nasal malignancies

From: Risk factors for nasal malignancies in German men: the South-German Nasal cancer study

 

Controls (%)

Cases (%)

OR (95% CI)

All study participants

   

Reference*

1815 (75.6)

281 (65.8)

1.0

Ever exposed for at least 1 year§

586 (24.4)

146 (34.2)

1.56 (1.17–2.01)

Per year of exposure§

586 (24.4)

146 (34.2)

1.02 (1.01–1.03)

Exposure (tertiles) < 7 years

198 (8.2)

44 (10.3)

1.57 (1.03–2.38)

7 < 20 years

183 (7.6)

37 (8.7)

1.23 (0.77–1.96)

20+ years

205 (8.5)

65 (15.2)

1.75 (1.19–2.58)

Smokers

   

Reference*

1064 (75.2)

185 (63.4)

1.00

Ever exposed for at least 1 year§

351 (24.8)

107 (36.6)

1.95 (1.34–2.83)

Per year of exposure§

351 (24.8)

107 (36.6)

1.02 (1.01–1.04)

Exposure (tertiles) < 7 years

123 (8.7)

31 (10.6)

2.08 (1.19–3.65)

7 < 20 years

116 (8.2)

25 (8.6)

1.45 (0.76–2.77)

20+ years

112 (7.9)

51 (17.5)

2.24 (1.31–3.82)

Never-smokers

   

Reference*

751 (76.2)

96 (71.1)

1.00

Ever exposed for at least 1 year§

235 (23.8)

39 (28.9)

1.06 (0.61–1.84)

Per year of exposure§

235 (23.8)

39 (28.9)

0.99 (0.97–1.02)

Exposure (tertiles) < 7 years

75 (7.6)

13 (9.6)

1.98 (0.84–4.65)

7 < 23 years

80 (8.1)

14 (10.4)

0.61 (0.22–1.67)

23+ years

80 (8.1)

12 (8.9)

0.96 (0.44–2.11)

  1. *never exposed to organic solvents.
  2. §daily/several days per week.
  3. Adjustments: Year of birth, community size, educational attainment, pack-years (all study participants), snuff package-years, years of exposure to hardwood dust, asbestos, use of nasal spray/nasal lavage and ever-use of insecticides in residences.